The first aircraft on an international flight since January, when the airport closed, landed in Wuhan, China, the first place where a new coronavirus was discovered in December 2019.
China drastically reduced its air connections with the rest of the world in late March to limit the spread of the virus.
That country has since largely suppressed Covid-19 by restricting movement, quarantine, testing, monitoring contacts and wearing protective masks. They record only a few new cases each day.
South Korean low-budget company T'way's plane landed at Tianhe International Airport on Wednesday with 60 passengers, state television CCTV reported.
According to footage released by the channels, passengers wore masks, and police officers also wore protective overalls and visors while checking passports.
According to official figures, close to 3,900 people have died from Covid-19 in Wuhan, or 80 percent of the 4,634 deaths in China.
The city has been in quarantine for more than two months since January 23. The city administration then organized tests for all 11 million residents.
China continues to ban almost all foreigners from entering national territory. Persons arriving in the country must be tested at their own expense and quarantined for 14 days.