While cannabis is becoming increasingly legal in more places, its uses and negative and positive impacts are becoming better known. THC (tetrahydrocannabinol), the main ingredient in cannabis, is well known for its effects on the brain, resulting in the "high" many users crave. However, cannabis like THC Gummies have the potential to alter your hormones, mainly through the pituitary, thyroid, and adrenal glands, as well as the reproductive system.
Hormones are produced in the bloodstream and then transported to receptor locations by these glands. They create changes in your body by binding to receptor sites in tissues and organs. These adjustments are necessary, and hormones are essential to physiological function. Hormones control body temperature, blood pressure, metabolism, sexual reproduction, growth, and mood/emotions, among other things. However, the problem arises when your body produces too many or too few hormones.
How Does THC Help With Hormonal Imbalance?
Endocannabinoids (ECS) are tiny molecules produced naturally in the body that act on cannabinoid receptors and function in various processes. CB1 and CB2 cannabinoid receptors exist in the body, and a few orphan receptors bind to endocannabinoids. THC binds to and activates these receptors as well. The ECS regulates fertility, pregnancy, hunger, mood, pain, memory, homeostasis, energy balance, and the immune system. Increased levels of endocannabinoids in the blood lead to the brain, where the ECS regulates locomotion via interaction with the cerebellum. In addition to creating runner's high, the ECS is responsible for the transduction of dopamine in the brain through dopamine release transduction.
Know About Hormonal Imbalance.
You'll have a hormonal imbalance when your hormones aren't functioning correctly. As a result, even the tiniest imbalance might have a cascade of unintended consequences. Hormone imbalance symptoms differ depending on which glands and hormones have been affected. Here are several signs that an imbalance is present:
- Excessive sweating
- Mood swings
- Vaginal atrophy
- Heavy or irregular periods
The following are the primary endocrine glands:
- The hypothalamus, pituitary, and pineal gland are all in the brain.
- The adrenal glands reside above the kidneys.
- The ovaries or testicles are located in the groin.
- Thyroid and parathyroid glands are located in the neck.
- The pancreas is located in the abdomen.
THC And Hormone Imbalance
- 1.Estrogen and THC
Estrogen hormones directly impact fertility, sexual development, and the risk of female-related diseases such as breast cancer. THC can potentially reduce estrogen levels, but additional research is needed. The tasty THC gummies may impact estrogen by boosting the activity of cytochrome p450 enzymes, commonly used to break down estrogen. It could be crucial as progesterone levels rise after ovulation to help fertilize.
LH and FSH are hormones that stimulate ovulation and, as a result, estrogen released by the ovaries. THC has proven to lower estrogen levels in breast cancer patients and postmenopausal women by inhibiting an enzyme called aromatase.
- 2.THC and Cortisol
Cortisol, the well-known stress hormone, alerts the body when anything stressful occurs. The adrenals produce cortisol in response to sensory information from the brain. Though tiny spikes in this hormone may be advantageous in an emergency, we don't want it hanging around daily.
Many factors might make us anxious, such as the fear of losing employment, arguments that endanger our relationships, or mounting bills. These stressors can result in prolonged cortisol production due to unresolved stress. THC has anti-anxiety properties, making it an ideal remedy for anxiety. THC can stop cortisol production by interrupting the stress response through CB1 receptors in the hypothalamus.
- 3.Thyroid and THC
Thyroid hormones TSH, T3, and T4 all play a role in thyroid function. Thyroid-stimulating hormone (TSH) controls hormone production, whereas T3 and T4 are linked to weight, energy, hair, skin, and nails, among other things. These hormones affect how we employ our metabolism to perform these tasks. Thyroid hormones are reduced by endocannabinoids, which minimizes the amount of energy required to achieve the necessary processes. THC can either stimulate or inhibit endocannabinoids, which could impact the thyroid. When endocannabinoids are blocked, TSH, T3, and T4 levels rise, possibly contributing to a more active thyroid.
THC's effects may differ depending on whether a person's thyroid is hyperactive, underactive, or expected. THC has been shown to boost levels of anandamide, a fatty acid neurotransmitter. Anandamide has also been reported to reduce TSH in hypothyroidism and normal thyroids with elevated TSH.
- 4.THC and Growth Hormone
Our bodies' growth and development are controlled by the growth hormone (GH). It is accomplished through cell reproduction and regeneration signals. Stronger bones, larger muscle mass, and more energy could result from increased growth hormone levels.
THC may affect Growth Hormone if used for a long time. A single dose has been demonstrated not to affect GH levels. Other cannabinoids, such as THC, have inhibited GH interacting with the CB1 receptor. Because THC binds to the CB1 receptor, it may also affect GH levels.
- 5.THC and Testosterone
Testosterone, like estrogen, aids in women's growth, maintenance, and repair of bone mass and reproductive tissues. It can also have an impact on one's behavior. A decrease in sex drive can be caused by a testosterone imbalance, especially in pre-and postmenopausal women.
The male and female reproductive organs produce testosterone in response to LH and FSH hypothalamic hormones. THC at high doses may impact LH and FSH levels, but additional research must confirm that it also affects testosterone levels. Some experts believe that THC is used in large dosages for an extended period without exercise. The inappropriate cannabis dosage may negatively affect testosterone.
Hormonal imbalances can affect everyone, and the complexity of these disorders can be intimidating. It's crucial to understand that good medicines do exist, even if choosing the correct one requires some trial and error. Seek medical advice, weigh your alternatives, and experiment, but rest that whether you decide on hormone replacement therapy (HRT), a lifestyle modification, or CBD, there will be a therapeutic option that is perfect for you.